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	Provedor de dados Anais da ABC (AABC) (1) Biol. Res. (1) Autor COUVE,EDUARDO (1) KRSULOVIC,JUAN (1) RONCAGLIOLO,MANUEL (1) TARDY,MARCIENNE (1) Palavra-chave Astrogliosis (2) Demyelination (1) Dysmyelination (1) Laminin (1) Metalloproteinases (1) Myelin mutant (1) Neurite outgrowth (1) Neuro-glia interactions (1) Neuronal migration (1) Optic nerve (1) Taiep rat (1) Mais... Tipo do documento Info:eu-repo/semantics/article (1) Journal article (1) Ano 2002 (1) 1999 (1) País Brazil (1) Chile (1) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última Dysmyelination, demyelination and reactive astrogliosis in the optic nerve of the taiep rat Biol. Res. KRSULOVIC,JUAN; COUVE,EDUARDO; RONCAGLIOLO,MANUEL. Taiep is an autosomal recessive mutant rat that shows a highly hypomyelinated central nervous system (CNS). Oligodendrocytes accumulate microtubules (MTs) in association with endoplasmic reticulum (ER) membranes forming MT-ER complexes. The microtubular defect in oligodendrocytes, the abnormal formation of CNS myelin and the astrocytic reaction were characterized by immunocytochemical and ultrastructural methods during the first year of life. Optic nerves of both control and taiep rats were processed by the immunoperoxidase method using antibodies against tubulin, myelin basic protein (MBP) and glial fibrillary acidic protein (GFAP). Taiep oligodendrocytes are strongly immunoreactive against tubulin, indicative of a significant accumulation of... Tipo: Journal article Palavras-chave: Myelin mutant; Taiep rat; Optic nerve; Dysmyelination; Demyelination; Astrogliosis. Ano: 1999 URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97601999000400005 Role of laminin bioavailability in the astroglial permissivity for neuritic outgrowth Anais da ABC (AABC) TARDY,MARCIENNE. The mechanisms involved in the failure of an adult brain to regenerate post-lesion remain poorly understood. The reactive gliosis which occurs after an injury to the CNS and leads to the glial scar has been considered as one of the major impediments to neurite outgrowth and axonal regeneration. A glial scar consists mainly of reactive, hypertrophic astrocytes. These reactive cells acquire new properties, leading to A non-permissive support for neurons. Astrogial reactivity is mainly characteriized by a high overexpression of the major component of the gliofilaments, the glial fibrillary acidic protein (GFAP). This GFAP overexpression is related to the astroglial morphological response to injury. We hypothesized that modulation of GFAP synthesis, reversing... Tipo: Info:eu-repo/semantics/article Palavras-chave: Astrogliosis; Neuro-glia interactions; Neurite outgrowth; Neuronal migration; Laminin; Metalloproteinases. Ano: 2002 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652002000400009 Registros recuperados: 2 Primeira ... 1 ... Última

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